Furosemide (Generic Lasix) is a loop diuretic causing fast and short diuresis. It possesses
natriuretic effect and also decreases levels of Cl- in blood, increases
excretion of K+, Ca2+, Mg2+. Penetrating into a renal tubule in
ascending thick limb of Henle's loop it blocks re-absorption of Na+ and
Cl-. Due to increased excretion of Na+ secondary intensified excretion
of water occurs and as well as increased secretion of K+ in distal part
of the renal tubule. Simultaneously excretion of Ca2+ and Mg2+
increases. Furosemide is used to treat edema syndrome in patients with
chronic heart failure (degree II and III), cirrhosis, diseases of
kidneys, acute heart failure (pulmonary edema), brain edema,
hypertensive crisis, arterial hypertension and others.
Dosage and direction
Take exactly as it was prescribed by your doctor.
Precautions
Before
using Furosemide, consult your doctor if you suffer from kidney
disease, liver disease, gout, lupus, diabetes, or an allergy to sulfa
drugs. Avoid becoming dehydrated as Furosemide makes you urinate more
often. Do not stop taking the drug even if you feel fine as high blood
pressure often has no symptoms. Avoid taking the drug if you are
pregnant or breastfeeding.
Contraindications
Hypersensitivity,
acute kidney failure with anuria, severe liver failure, liver coma and
precoma, stenois of urethra, acute glomerulonephritis, urinary tract
obstruction, precoma, hyperglycemic coma, gout, arterial hypotension,
heart attack, pancreatitis and others.
Possible side effect
Contact
your physician for medical attention if you have signs of allergy or
any of the following conditions: dry mouth, thirst, nausea, vomiting;
weakness, drowsiness, restless, or light-headed, fast or uneven
heartbeat, muscle pain, less than usual urination or absence of
urination, easy bruising or bleeding, red blistering skin rash, hair
loss.
Drug interaction
Hearing damage may occur if
Furosemide is administered with aminoglycoside antibiotics (gentamicin
and others) or Edecrin - another diuretic. Concomitant use of Furosemide
and aspirin may cause high blood levels of aspirin and aspirin
toxicity. Furosemide is able to reduce excretion of lithium by the
kidneys. Sucralfate (Carafate) reduces the action of Furosemide. Intake
of Ingestion of Furosemide and Sucralfate should be separated by two
hours.
Missed dose
The medication is sometimes
administered for single use so you will not need a dosing schedule. If
you take Furosemide regularly and forgot to take a dose, take it as soon
as you remember. Skip the missed dose if it is almost time for the next
intake. Resume your regular schedule. Do not compensate the missed dose
by taking an extra one.
Overdose
In case of loss of
appetite, ringing in ears, severe weakness, dizziness, confusion,
lightheadedness, or fainting, seek for immediate doctor's attention.
Storage
Keep away from children at room temperature in a dry and dark place.
Disclaimer
We
provide only general information about medications which does not cover
all directions, possible drug integrations, or precautions. Information
at the site cannot be used for self-treatment and self-diagnosis. Any
specific instructions for a particular patient should be agreed with
your health care adviser or doctor in charge of the case. We disclaim
reliability of this information and mistakes it could contain. We are
not responsible for any direct, indirect, special or other indirect
damage as a result of any use of the information on this site and also
for consequences of self-treatment.